Invasive Fusariosis: A Single Pediatric Center 15-Year Experience.

Invasive Fusariosis in the Voriconazole Era: Single-Center 13-Year Experience

Background.  Invasive fusariosis remains an aggressive, albeit infrequent infection in immunocompromised patients. Methods.  We identified all cases of invasive fusariosis between January 2002 and December 2014. We recorded patient characteristics including clinical presentation, treatment, and outcomes at 6 and 12 weeks after diagnosis, as well as species identification and antifungal drug sus...

Earlier Diagnosis of Invasive Fusariosis with Aspergillus Serum Galactomannan Testing

Cross-reactivity of Fusarium species with serum galactomannan antigen (GMI) test has been observed. We sought to evaluate if GMI could help to early diagnose invasive fusariosis and to monitor treatment response. We reviewed the records of all patients with invasive fusariosis between 2008 and 2012 in three Brazilian hospitals. We selected patients who had at least 1 GMI test within 2 days befo...

Inherited Classical and Alternative Pathway Complement Deficiencies in Children: A Single Center Experience

Clinical Characteristics of Pediatric Esophagitis in Southern Iran; A Single-Center Experience

Background: We sought to determine the clinical characteristics of pediatric esophagitis in southern Iran. Methods: This cross-sectional study was conducted over a 4-year period, from 2005 to 2009, in Nemazee Hospital, a tertiary healthcare center in Shiraz, southern Iran. We consecutively included all pediatric patients (< 18 years) who underwent endoscopy in our center and had pathology...

Fusarium, a significant emerging pathogen in patients with hematologic malignancy: ten years' experience at a cancer center and implications for management.

Despite increasing reports of life-threatening Fusarium infections, little is known about its pathogenesis and management. To evaluate the epidemiology, clinicopathologic features, and outcome of invasive fusariosis in patients with hematologic cancer, we conducted a retrospective study of invasive fusarial infections in patients with hematologic malignancy treated at a referral cancer center o...